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Re: Cymbalta (duloxetine) - report » SLS

Posted by KaraS on August 21, 2004, at 16:48:17

In reply to Cymbalta (duloxetine) - report, posted by SLS on August 21, 2004, at 8:13:25

> Cymbalta (duloxetine)
>
>
> 8/10/2004
>
> I began to taper my dosage of imipramine from 300mg
>
> --
>
> 8/17/2004
>
> I took my last 50mg dose of imipramine
>
> I am experiencing a mild rebound improvement of depression that is the direct result of discontinuing imipramine so quickly. This is normal for me.
>
> --
>
> 8/20/2004
>
> Begin Cymbalta...
>
> First dose - 30mg
>
> I experienced a brief significant improvement in depressive symptoms beginning 1 hour after this first dose. It lasted for 3 hours. No side effects.
>
> --
>
> 8/21/2004
>
> Second dose - 30mg
>
> I did not experience any improvement. No side effects.
>
> --
>
>
>
> * The manufacturer's label describes initiating treatment with Cymbalta using the desired target dosage. People are to begin by taking 40-60mg per day. Dosing is probably best split as twice a day. The half-life of Cymbalta is approximately 12 hours.
>
> * My doctor asked that I take 30mg for the first week before moving up to 60mg in the second week. I am impatient, of course, but this is probably prudent, especially after having so recently discontinued imipramine.
>
> * Smiling
>
>
> - Scott
>


I'm so glad it's going well so far. My thoughts are with you...

-Kara


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URL: http://www.dr-bob.org/babble/20040821/msgs/380487.html