Posted by Ktemene on July 9, 2004, at 23:10:13
In reply to Parnate or Nardil is there a difference? HELP, posted by bluebird on July 6, 2004, at 11:24:00
> Just looking for some input from those of you that have taken Parnate and Nardil. What is the difference and which is the best way to go? I have read many articles and info about them and opinions vary. Some say Nardil is the very best and others say start with Parnate it has less side effects. I will be taking it for severe SAD, depression, and avoidant personality disorder. Presently taking Paxil and in the process of going off of it. Not easy to do. Anyones input would be greatly appreciated
> Thanks, bluebirdBoth are very effective medications as a great number of posters on PB have attested. My sense from reading a lot of posts is that Parnate is more activating and less likely to cause weight gain and sexual dysfunction and some other unpleasant SE's. But Parnate does tend to cause greater sensitivity to tyramine, so it requires more vigilance in keeping to the diet restrictions. Parnate is more apt to be helpful for people who also suffer from ADD. Nardil is more forgiving in respect of the diet restrictions (although great care is still required) but more likely to cause SE's. Nardil is also more apt to be helpful for people who have problems with social phobia and other anxiety-related conditions and it is less likely to cause insomnia. There is another MAOI, Selegiline/Deprenyl, that has been discussed a lot because it may soon be released in a transdermal patch form that will more or less eliminate the need for diet restrictions. Selegiline seems to resemble Parnate in being quite activating. When taken orally in doses no greater than 10mg per day Selegiline is preferential for MAO-B, so the diet restrictions can be ignored. But if the oral dose of Selegiline is over 10mg per day then the diet restrictions apply.
You’ve probably already come across the article that Current Psychiatry did on MAOI’s a couple of years ago but just in case I’ll include the URL: http://www.currentpsychiatry.com/2002_06/06_02_maoi.asp
There are a huge number of helpful thoughtful posts on the MAOI’s that you can find by searching, but I have put a few of the ones I found particularly useful below (in no special order).
Nardil:
Gardenergirl http://www.dr-bob.org/babble/20040429/msgs/342284.html
King Vulcan http://www.dr-bob.org/babble/20040627/msgs/361348.html
Parnate:
Harryp http://www.dr-bob.org/babble/20040505/msgs/344714.html
Cubbybear http://www.dr-bob.org/babble/20030106/msgs/135041.html
Cybercafe http://www.dr-bob.org/babble/20040429/msgs/341663.htmlSelegiline:
Elleff http://www.dr-bob.org/babble/20040614/msgs/357474.html
poster:Ktemene
thread:363467
URL: http://www.dr-bob.org/babble/20040704/msgs/364581.html