Posted by theo on July 4, 2004, at 17:33:46
In reply to Re: What really is the most potent antidepressant?, posted by KaraS on July 4, 2004, at 15:06:23
I don't have a link readily available but several studies state this. The problem with Effexor XR is that its dose range is so broad, 37.5mg to 225mg, and you don't get NE effects until you hit arond 150mg. It'll be nice when Cymbalta comes out so you can get the benefit of a med that hits 5H-T & NE at starting dose. Effexor doesn't work as a combo until you reach high mg's. Also, stopping Effexor XR is worse than stopping an SSRI so the more you go up in dose, the longer it takes to stop it, and with Effexor every time you go down in dose you get full blown discontinuation syndrome.
poster:theo
thread:362860
URL: http://www.dr-bob.org/babble/20040704/msgs/363088.html