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Re: Seroquel Qstns- urgent » SLS

Posted by Sad Panda on July 4, 2004, at 10:23:54

In reply to Re: Seroquel Qstns- urgent » Sad Panda, posted by SLS on July 4, 2004, at 9:28:57

> Hi Panda.
>
> > Zyprexa & Remeron are non-selective 5-HT2 antagonists while Seroquel is much more selective at blocking 5-HT2A only while having much less effect on 5-HT2C receptors. 5-HT2C antagonism increases appetite.
>
> What effects does Seroquel have on 5-HT1a receptors? Another poster suggested that it was an antagonist. A few Medline abstracts suggested it was an agonist. My girlfriend is experiencing a robust and sustained antidepressant effect from Seroquel 700mg. I have become interested in trying this myself. According to the BNN newsletter, a recent study determined that Seroquel monotherapy 300-600mg was effective for treating bipolar depression. Interesting.
>
> Thanks.
>
>
> - Scott
>

Hi Scott,

I don't know. :) I am mostly facinated buy things that block 5-HT2A since it seems to be the cornerstone of most of the AP's, TCA's & alot of migraine prevention drugs.

I will investigate however :)

Cheers,
Panda.



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