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Re: Seroquel Qstns- urgent » Sad Panda

Posted by SLS on July 4, 2004, at 9:28:57

In reply to Re: Seroquel Qstns- urgent, posted by Sad Panda on June 30, 2004, at 1:20:30

Hi Panda.

> Zyprexa & Remeron are non-selective 5-HT2 antagonists while Seroquel is much more selective at blocking 5-HT2A only while having much less effect on 5-HT2C receptors. 5-HT2C antagonism increases appetite.

What effects does Seroquel have on 5-HT1a receptors? Another poster suggested that it was an antagonist. A few Medline abstracts suggested it was an agonist. My girlfriend is experiencing a robust and sustained antidepressant effect from Seroquel 700mg. I have become interested in trying this myself. According to the BNN newsletter, a recent study determined that Seroquel monotherapy 300-600mg was effective for treating bipolar depression. Interesting.

Thanks.


- Scott

 

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