Re: Nardil, SNRIs, tyramine, hypertension

Posted by Ilene on May 31, 2004, at 7:18:29

In reply to Re: Nardil, SNRIs, tyramine, hypertension, posted by Questionmark on May 30, 2004, at 18:57:08

> Reboxetine and other NRIs do not inhibit norepinephrine release. They inhibit the reuptake of NE, allowing MORE to be available in the synapse. The reason they help prevent hypertensive reactions from MAOIs is that tyramine gets into NE-releasing neurons via the reuptake pumps, and so less tyramine is able to be absorbed into neurons because the reuptake pumps are blocked.
I've read that NE is also a pressor amine, so I'm not sure how much of an advantage this would be. Has anyone taken an NRI and an MAOI?
The Straterra drug information says *not* to take it within 2 weeks of taking an MAOI. I realize from experience that the patient information is not always accurate.
I.

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Nardil, SNRIs, tyramine, hypertension Michael Bell 5/29/04
Re: Nardil, SNRIs, tyramine, hypertension » Michael Bell btnd 5/29/04
Re: Nardil, SNRIs, tyramine, hypertension » btnd Michael Bell 5/29/04
Re: Nardil, SNRIs, tyramine, hypertension Ilene 5/29/04
Re: Nardil, SNRIs, tyramine, hypertension » Ilene Michael Bell 5/29/04
Re: Nardil, SNRIs, tyramine, hypertension TheOutsider 5/30/04
Re: Nardil, SNRIs, tyramine, hypertension Questionmark 5/30/04
Re: Nardil, SNRIs, tyramine, hypertension Ilene 5/31/04

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