Posted by Ilene on May 29, 2004, at 21:28:27
In reply to Nardil, SNRIs, tyramine, hypertension, posted by Michael Bell on May 29, 2004, at 13:51:37
> It's amazing to me that one of the best meds for SP is so hard to attain and stay on b/c of hypertensive risk. I'm not that knowledgeable about chemistry, but isn't there some kind of substance that someone can ingest to take over MAO's role of break down tyramine? Sort of like taking lactaid pills for people who can't break down lactic acid properly. Then someone on Nardil or Parnate can take that substance along with the MAOI to help prevent hypertensive crisis.
>AFAIK there isn't anything like that, because it would interfere with the MAOI's mode of action. There are drugs you can take after the fact, but I think the majority of MAOI users don't have a problem as long as they are careful about what they eat and the other drugs they take. The biggest dietary no-no is aged cheese, which is pretty easy to avoid.
> Moreover, I remember reading a study which concluded that since SNRIs (Reboxetine, Strattera) inhibit norepinephrine release, taking it with MAOIs may lessen the risk of hypertensive crisis. Does anyone have knowledge or personal experience with this combo?
I don't understand how this would work. I'd be interested in this study.
I.
poster:Ilene
thread:351877
URL: http://www.dr-bob.org/babble/20040527/msgs/351993.html