Posted by platinumbride on May 24, 2004, at 11:30:15
In reply to Re: selegiline + dopamine increase ?, posted by Ilene on May 24, 2004, at 9:00:41
Hi, and thank you all so much for yur input.
As far as updates on tis sttudy, all I know is tht my doc read of some similar study done within at least the past 4 years, in some psychiatric journak in America (I forgot the name....memory sucks due to either depression, anxiety or being in the middle of a neurontin dose). That was teh basis of his prescription.
Personally, I am sick of trying "natural" remedies, as I have had no success with tthem, and have been trying them even before the 8 yers or so tht I have been on the chemical route, but one must keep an open mind...
I would have preferred parnate or marplan, but he just won't do it. Very worried about the high doses required, the dietary and med interaction issues and a patient who came to him fresh from the hospital with a botched suicide attempt.
I just want to say one more thing:
My insurance company has some ridiculous way of deciding what drugs it will assign a low co-pay to. They SAY that it is based on their research of the best drugs available to treat conditions. Sooooo, seligeline is an "approved" drug in their book for PARKINSONS, so I just pay a nominal co-pay for it, as it is generic. Nardil and parnate have very high co-pays. To get marplan, the doc has to write a friggin' dissertation! I was pretty shocked at that one. You cant even get ambien without a song and dance from the doctor, because their modern hypnitic of choice is sonata. Same with abilify or seroquel, because they like zyprexa or risperidol.
Sorry to rant, but, parnate and nardil are generics!!!!
Anyway, I guess the shot in the dark with this will begin today IF my pharmacy has managed to get seligeline in stock....
many many thanks,
Diane
> > L-deprenyl plus L-phenylalanine in the treatment of depression
> >
> > Birkmayer, W
> >
> > J Neural Transmission. (AUSTRIA), 1984, 59/1 (81-87)
> >
> > ABSTRACT
> >
> > The antidepressive efficacy of deprenyl (5-10 mg daily) plus L-phenylalanine (205 mg/day) has been evaluated in 155 unipolar depressed patients. Both oral and intravenous administration showed beneficial effects in 90% of outpatients and 80.5% of inpatients. It is concluded that this combined treatment has a potent antidepressive action based on the accumulation of L-phenylethylamine in the brain.
> >
>
>
> Because this study is 20 years old I thought there would be some follow-up, so I went into Medline and looked. I found very little, except about Parkinsons Disease. Looks like this research went nowhere. I wonder why. Someone with access to an academic library might look in the Science Citation Index/Web of Science.
>
> I.
>
poster:platinumbride
thread:349899
URL: http://www.dr-bob.org/babble/20040521/msgs/350125.html