Posted by jlbl2l on May 10, 2004, at 17:37:24
In reply to Re: neurontin and the Ca or Mg thing.... » chemist, posted by chemist on May 10, 2004, at 12:20:34
chemist, thank you for your help.
i thought about adding a chelate of calcium could do something in theory since we are dealing with calicum channels - neurontins mech of action.
my questions :
I had 1 grand-mal seizure so it is possible i am prone to seizures. since magnesium increases the seizure threshold, does calcium lower it? this could be dangerous if i were to take high amounts.
second, should i take the calcium and neurontin at the same time, or take the calcium before (im assuming before....) and also, i imagine the larager the dosage, the more likely success i would have in it getting to my brain. what dosage would you suggest.
third, your suggestion of antacids is a nice thought, but for neurontin, it is contradicted as well as magnesium as it lowers its absorption quite a bit (it states this on the prescricing information) I would need to let 2 hours elapse at least. Also, I was planning to do this all on an empty stomach.
fourth, in theory, what is the best carrier for calcium to the brain rather than other parts of the body (we already discussed dosages above). I prefer not glutamate or glutamine chelates as my seiure threshold could be lowered. magnesium glycinate is known for one of the best absorbption rates from the gut to prevent "the runs" perhaps there is a chelate of calcium glycinate, though i dont know chemistry.
Finally, this theory esentially involves adding calcium to the calcium channels in the brain to make neurontin more effect, or at least help me lost some of its tolerance? Is this really a good option?
I've told my story in the first post, which is why this baffles me so much. Oh, and chemist, don't always rely on pubmed studies to confirm everything, a lot of what is out there can be found on the net through personal tetimonais and message boards, and any help I can get is apperciated, if studies can't find it..
all the best :-)
jlbl2l
poster:jlbl2l
thread:345062
URL: http://www.dr-bob.org/babble/20040510/msgs/345505.html