Posted by TEDAR on May 1, 2004, at 13:02:58
In reply to Re: klonopin » Tedar, posted by chemist on April 25, 2004, at 21:53:15
> > To Chemist: you mentioned in previous post to get off Klonopin cold turkey and get switched to ativan or Valiun long term. Why?
>
> hi tedar...klonopin is notorious for tolerance at about 6 months. valium - although it has suffered a bad rap since valley of the dolls - is quite excellent for long-term treatment, with little to no need for increased dosage, and is the second-oldest benzo on the market. ativan i recommend as an alternative, with a slower onset of action (for prn dosing ONLY) than valium, and tolerance does not seem to be a problem in the literature i have perused. to be frank, klonopin is a long, slow ride that halts after a while. valium continues to do the job - and alleviates the need for xanax, for instance - due to long half-life of elimination. ativan has a shorter retention time in your system, but again, i come back to (in my experience) no need for ramping up the dose....hope this is of help, and all the best, chemistKlonopin and valium have similar Brain pathway dynamics-very lipophilic. And with Valium being biphasic with its half life, the problem in the past existed with the initial buzz 20 minutes after administration, followed by a more stable pattern of brain levels. Valley of the Dolls was not the only reason. People liked the buzz and the conscious sedation. While I think Valium is a good med, a lot of psychs feel that Klonopin offers more predictable therapeutic effects, without the more rapid lipophilic related buzz that Valium gives..I appreciate your further thoughts. Maybe, I am missing something.
poster:TEDAR
thread:339715
URL: http://www.dr-bob.org/babble/20040429/msgs/342205.html