Posted by King Vultan on April 24, 2004, at 11:02:55
In reply to anyone ever combine REMERON and MAOI????, posted by ace on April 24, 2004, at 0:59:52
> Never have seen this done, thats why im a bit reluctant to try it at the moment....so has anyone out their ever tried remeron with an maoi??
>
> if so, what was it like??
>
>
> Thankyou guys!
> Ace.No, I haven't personally, but it is safe. I typically use the excellent receptor chart in "Psychotropic Drugs", which is based on the classic Seeman and Richelson studies from the 90's. Remeron's major effect is a powerful histamine H1 blockade, followed by a serotonin 5-HT2 blockade. The next one is an alpha-2 adrenergic blockade, which IMO, is only problematic if it is a major effect of a drug, as it is in yohimbine. In Remeron, the effect is approximately two orders of magnitude below that of the histamine blockade and should not be a problem.
I've been having trouble sleeping on Nardil and considered Remeron but decided to go with trazodone because of its much shorter half life. Remeron appears to have more daytime sedation and weight gain problems. I just saw my doctor yesterday and discussed the issue of sleep aids in some detail. He gave me a trazodone prescription for 2 x 50 mg and had me start at 25 mg last night, and even that effected an improvement over what I have been experiencing, which is two to three hours of sleep a night.
Todd
poster:King Vultan
thread:339422
URL: http://www.dr-bob.org/babble/20040423/msgs/339506.html