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Re: Quitting benzos cold turkey

Posted by chemist on April 9, 2004, at 23:55:28

In reply to Re: Quitting benzos cold turkey » silmarilone, posted by Sad Panda on April 9, 2004, at 11:12:21

> > Bullshit. I've withdrawn from both, and Paxil was FAR worse than klonopin. Klonopin was fairly mild and lasted 2 weeks. WD from Paxil lasted almost 4 months and I never wanted to kill myself more. And I had been on Paxil for less time, and at a lower dose.
> >
> > thomas
> >
> >
> > >
> > > Trust me...withdrawaling from Paxil, effexor, etc. pales in comparison to Klonopin withdrawal...
> >
> >
>
> Actually, Kolopin withdrawl is worst for most people. About 5% of the population have a gene which gives them extra amounts of the enzyme CYP-2D6 which is used to metabolise Effexor, Paxil & Luvox, this makes them ultra fast metablisers of these drugs & they suffer very badly from withdrawl. So the people who moan loudly about Paxil & Effexor withdrawl are a small minority and should benefit greatly from using Prozac to help taper off.
>
> The other thing that makes Klonopin withdrawl worse is the fact that it can kill you, where as Paxil withdrawl can't.
>
> Cheers,
> Panda.
>
>
>
hi there...hepatic metabolism of effexor, for instance, is indeed via the CYP2D6 isoenzyme, although you needn't worry about 1,4-benzodiazepines interfering with clearance: it is far more troublesome if you are taking a tricyclic. now, getting to the heart of the matter, it is absolutely forbidden to go cold-turkey on any benzo or derivative (xanax) in that (as the previous poster stated correctly) this can lead to seizures and, in extreme circumstances, death. taper, taper, taper...chemist


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