Posted by Stan on March 24, 2004, at 1:03:03
In reply to Re: Dopamine Agonists Mirapex, posted by Keith Talent on March 23, 2004, at 23:34:58
> I would have thought that the problem with such a specifically-acting drug like Mirapex would be tolerance. Has anyone successfully used this day in, day out for months or years?
>--------------------------------------------
i've been taking mirapex or requip for a couple of years to combat 'restless legs syndrome.' over this period i've gradually had to quadruple the dose i started with in order to maintain the same benefits. when i take mirapex i use .5 mg four times daily for a total of 2.0 per day, while requip requires 1.0 mg four times daily for a total of 4.0. i rotate them every six months or so, switching from mirapex to requip and vice versa in an attempt to gain a fresh response. the side effects (for me: upset stomach but no nausea, drowsiness, fatigue, lethargy) have never subsided.....parkinson's patients take higher dosages.....i don't know how they do it without passing out.
to the poster who asked about amantadine...hmmm....if i've got the name right, and i'm speaking strictly from memory, this is an antiviral drug primarily used to fight off influenza. i wasn't aware that it had any positive impact on mood disorders, but i don't keep up with medical research.
stan
poster:Stan
thread:327293
URL: http://www.dr-bob.org/babble/20040319/msgs/327599.html