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Re: Dopamine Agonists Mirapex

Posted by King Vultan on March 23, 2004, at 8:00:55

In reply to Dopamine Agonists Mirapex, posted by bertill33 on March 23, 2004, at 3:57:11

> I am 25 have struggled with depression for 5 terrible years. I have been able to get out of major depression but even on meds that do not cause sexual problems I have no sex drive or function at all. It is getting extremly worrisome. I am hearing I should try mirapex or even deprenyl. Who has some good experience with dopamine based drugs. Wellbutrin did nothing for me. What is even worse is I have little motivation or emotional response. But the major depressive symptoms of pain, sadness and misery are treated.


I've had similar experiences on the drugs I've tried, including Wellbutrin, and have similar sexual issues. I was considering trying a dopamine agonist but thought I would try the MAO inhibitors first, as they are a more conservative approach IMO. I've read a great deal about dopamine agonists, and while they do work for some people, they also commonly cause nausea and/or somnolence. In fact, one of the major uses for the stimulant Provigil is to treat Parkinson's patients falling asleep in the middle of the day from their dopamine agonists.

I decided to try the MAOI Nardil first, but the other one, Parnate, is considered to be a more pro-sexual drug. It is very dopaminergic and more powerful than Wellbutrin as an antidepressant, while also being quite activating, which I do not believe you would find a dopamine agonist to be. It has dietary restricitions which scare away many people, but these are rather overblown. Certain drug combinations must be avoided, however.

Todd


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poster:King Vultan thread:327293
URL: http://www.dr-bob.org/babble/20040319/msgs/327312.html