Posted by Cruz on March 21, 2004, at 18:01:18
In reply to Re: Sleep deprivation, posted by zeugma on March 21, 2004, at 15:37:26
For many years I used sleep deprivation to escape from depression. After 2 nights without sleep, I would resume sleeping from 9 pm to 5 am the depression would stay away for exactly 2 weeks.
When it returned I would forgo sleep for 2 nights again. This repeatedly worked until I had a motorcyle accident in which my testicle were severely bruised. Ever since then sleep deprivation is not effective. The evidence is that my Sertoli cells that produce Inhibin B were damaged in the accident. It's just my own theory at this point, but I am convinced Inhibin B is what is responsible for the antidepressant effect of sleep deprivation. As of now the wide spread belief of researchers is that the only function of Inhibin B is surpressing FSH. Back in 1992 a study was done at the U of Washington by Bremner and McGlocklin in which they concluded that with the levels of Inhibin B that they measured in brain and spinal fluid, it must have a more significant role in the CNS. That conclusion seems to be overlooked. Particularly by researchers doing studies of mood disorders in women. They routinely note a markedly reduced level of Inhibin B in depressed cases, but consider it not a factor because Inhibin B only surpresses FSH. Wrong! Eventually some research group will wake up and smell the coffee.
poster:Cruz
thread:326021
URL: http://www.dr-bob.org/babble/20040319/msgs/326775.html