Posted by rod on March 6, 2004, at 10:11:27
In reply to Re: Dosage of Galantamine for non Alzheimer Purpos » rod, posted by SLS on March 6, 2004, at 9:26:44
> > And maybe some kind of subsyndromal epilepsy, because of hypoperfusion. Also the temporal lobe. This might explain my ADD symptoms and why I get worse on SSRIs (Temporal Lobe ADD).
>
> Hmmm. How are these things linked? How does the temporal lobe relate to SSRI-induced exacerbation of your depression?
>http://www.mindfixers.com/amensub5.html
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Temporal Lobe ADD, according to Dr. AmenIn my clinical experience, temporal lobe symptoms are found in approximately
10-15% of patients with ADD. Temporal lobe symptoms can be among the most
painful.These include periods of panic or fear for no specific reason, periods of
spaciness or confusion, dark thoughts (such as suicidal or homicidal
thoughts), significant social withdrawal, frequent periods of deja vu,
irritability, rages, and visual changes (such as frequently seeing shadows
out of the corner of the eye).Temporal lobe dysfunction may be inherited or it may be caused by some sort of
brain trauma.Temporal lobe symptoms associated with ADD are often very responsive to
anti-seizure medication, such as Depakote, Neurontin or Tegretol. Temporal
lobe symptoms are often made worse by serotonergic medications such as
Prozac, Paxil, Zoloft, etc.
-----------------------------------------http://www.brainplace.com/bp/atlas/ch12.asp
4. Temporal lobe ADD, with symptoms of inattention and/or hyperactivity-impulsivity and mood instability, aggression, mild paranoia, anxiety with little provocation, atypical headaches or abdominal pain, visual or auditory illusions, and learning problems (especially reading and auditory processing). Brain SPECT imaging typically shows decreased or increased activity in the temporal lobes with decreased prefrontal cortex activity. Aggression tends to be more common with left temporal lobe abnormalities. This subtype typically responds best to anticonvulsant medications (such as gabapentin, divalproate, or carbamazepine and a psychostimulant.
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Epileptic discarges are somehow related to hypoperfusion. Hypoperfusion may cause the nerves to fire out of control. That might be the eason why people with temporal ADD respond to anticonvulsant medication. Neurontin increases attention and memory with me. And I get worse on SSRIs. I dont know why it is that way.The symptoms mentioned for this subgroup also fit the "indicators suggestive for subsyndromal epilepsy" http://www.dr-bob.org/tips/isse.html
But its no longer there...I think these two conditions are somewhat the same or at least overlap to a high degree.
> The following drugs made me feel moderately or severely worse:
> moclobemide (Manerix, Aurorix)
neutral
> protriptyline (Vivactil)
never tried
> bupropion (Wellbutrin)
worse
> topiramate (Topamax)
never tried
> tiagabine (Gabitril)
never tried
> triiodothyronine (Cytomel)
never tried
> amoxapine (Asendin)
never tried
> mirtazepine (Remeron)
worse
> idazoxan (investigational)
never tried
BTW, good luck with Memantine!Roland
poster:rod
thread:320016
URL: http://www.dr-bob.org/babble/20040304/msgs/321092.html