Posted by missliz on January 29, 2004, at 2:17:03
In reply to Re: Possible? To Nardil from Parnate?, posted by Maxime on January 27, 2004, at 17:41:35
A lot of people need more than 60 mg- which blows my mind, because I was booming on 30 mg. Parnate doesn't "poop out". The stuff is basicly methamphetamine, with a few other choice metabolites. It works- you just need enough of it. There's a bonafide problem of undermedication of deppressive illness in this country- it's 'cause the PDR is written by company lawyers. What people on this board call poop out is usually just time to titrate the dose up again but the bottom of the class people who get shunted into psych won't do it. May I suggest a second opinion? Or a new doctor?
If he switches, he needs to taper the dose down for a few weeks and then do the two weeks. The chemistry is too tedious to write out- but there is any ruler of the MAOI it's me. The washout is very important. Gruesome, but better than stroking out.
Parnate is manufactured from amphetamine; Nardil is made from antibiotics, which were the original MAOIs. It's gentler, causes weight gain in some people, I LOVED it. So good to be normal! Drank gallons of coffee on it, but I was in grad school a lot of that time. The lifestyle.
I think a higher dose deserves a chance- or, here's a cool trick, you can goose an MAOI with lithium and see if that gets it moving. I reccomend Lithobid over the generic, a small dose should do it. Do not under any circumstanses take a diuretic with this combo- Parnate and thiazide diuretics are potentially lethal. Bet nobody knew that, did you? ;D Neither does your shrink- it isn't in the PDR, but it's in the formularies of every other nation in the first world.
If the shrink doesn't know any of this, he's in over his head and you need a real psychopharmacologist. MAOIs are the big leagues of treatment, and depression that severe needs a doc who knows what he's doing.
Is he on anything else?
This is all meant to be tried under the supervision of a pdoc who knows what they're doing, of course, but there are more things to try with the Parnate. Good luck.Lizzy
poster:missliz
thread:305978
URL: http://www.dr-bob.org/babble/20040127/msgs/306768.html