Posted by jerrympls on January 20, 2004, at 23:21:03
In reply to Dopamine system out of whack? » jerrympls, posted by Karen Moore on January 20, 2004, at 22:51:23
> Jerry,
> Have you tried MAOI's? Parnate seems to be the most dopaminergic. I also have the same suspicion about my own "atypical" treatment resistant depression being dopamine based. I feel terrible on serotonergics and only feel better with stimulants. Right now I'm getting by on Adderall but I have to alternate days, 3 on 2 off, because by day three my blood pressure drops and I feel absolutely wasted. But at least I have 2 or 3 days a week when I can function.
> Endocrine abnormalities can also effect dopamine, if you haven't already gone down that route...
> I'm also very curious about the opiates, which one's have you tried?
> KMHello!
Yes, I've been on Nardil and it worked really well for about a month - but then everything went downhill and the side effects were horrible. I've also had a full endocrine work-up. As far as opiates - I've only been on hydrocodone and Propoxyphene. I was on Dilauded for about a week in the hospital during a bout of encephalitis and was given a short supply of Percocet (oxycontin) after being released.
Recently my pdoc agreed to put me on Vicodin (hydrocodone) 4 tabs/day. However, it was causing anxiety more than anything - which is odd because it has always gotten me out of the most severe depressions. I stopped it for a while and now it's working a little. I've heard a little about bromocriptine and buphenorine - but I am unsure my doc will want to try those...
I'm just at the end of my rope with SSRIs/SNRIs...it's my dopamine system I'm sure of. I'm so apathetic, lethargic and without pleasure it's killing me...I see my doc on Thursday so we'll see...
poster:jerrympls
thread:303487
URL: http://www.dr-bob.org/babble/20040118/msgs/303515.html