Re: Ach(M) is this the dumb receptor

Posted by Interject79 on January 16, 2004, at 13:08:52

In reply to Re: Ach(M) is this the dumb receptor, posted by rod on January 15, 2004, at 8:01:57

Sorry to be confusing. Ach (N) antagonism in general does negatively impact cognitive performance, so I think the nicotinic Ach receptors are the 'cognition' ones primarily. You're right about this. But there are some muscarinic Ach receptors which, when antagonised, negatively impact cognition as well. I think M1, which Zyprexa antagonises, is one of these. I'm not certain, but I don't think Zyprexa does much to the nicotinic receptors. It's anticholinergic effects are muscarinic.
This might just confuse more. What we might think is that Zyprexa isn't as bad on cognition as it could be, with relation to acetylcholine. Dopamine's another issue...
Best,
interject

Thread

Ach(M) is this the dumb receptor linkadge 1/14/04
Re: Ach(M) is this the dumb receptor SLS 1/14/04
Re: Ach(M) is this the dumb receptor Keith Talent 1/14/04
Re: Ach(M) is this the dumb receptor SLS 1/14/04
Re: Ach(M) is this the dumb receptor Pam DaMonium 1/14/04
Re: Ach(M) is this the dumb receptor Interject79 1/15/04
Re: Ach(M) is this the dumb receptor rod 1/15/04
Re: Ach(M) is this the dumb receptor Interject79 1/16/04

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