Posted by Shawn. T. on October 14, 2003, at 0:02:31
In reply to Re: BIG differences between benzos? » Shawn. T., posted by Viridis on October 12, 2003, at 3:29:23
I couldn't locate any research that involved identifying lorazepam's binding profile. One common problem with lorazepam is amnesia, but low doses should usually avoid this problem. You could also look into temazepam (Restoril); it has a somewhat shorter half-life than lorazepam. I don't know anything about its binding profile either. In general, it's safe to assume that most benzodiazepines (other than drugs like zolpidem) are nonselective for alpha subunits. However, do not assume that they're all equally effective at all subtypes of GABA-A receptors.
Shawn
poster:Shawn. T.
thread:266360
URL: http://www.dr-bob.org/babble/20031010/msgs/269175.html