Posted by Viridis on October 12, 2003, at 3:29:23
In reply to Re: BIG differences between benzos? » Viridis, posted by Shawn. T. on October 9, 2003, at 23:20:49
Hi Shawn,
Many thanks for the helpful info and links. I was skeptical, too, about the idea that structural differences would automatically invalidate the hypothesis of cross-tolerance between clonazepam and alprazolam. I'll relate this to my pdoc, who is very open-minded and doesn't mind being contradicted. He actually loves to learn about how these meds work, which is very refreshing.
So, my next question is: what do you know about Ativan (lorazepam)? I seem to need a fast-acting, short half-life benzo occasionally, and since I've apparently developed some tolerance to alprazolam (despite only sporadic use), might this be a valid substitute for alprazolam (e.g., is its subunit binding profile more selective)? I've never tried it, but am thinking of asking my pdoc for a trial prescription, perhaps to alternate with Xanax.
Any insights would be much appreciated.
Best,
Viridis
poster:Viridis
thread:266360
URL: http://www.dr-bob.org/babble/20031010/msgs/268592.html