Posted by JonW on September 23, 2003, at 0:09:46
In reply to Re: Parnate, posted by cubbybear on September 20, 2003, at 5:05:09
> I'm one of those who tried Moclobemide and stayed on it for about 6 weeks, the conventional "kicking in" period for ADs. The way I view this drug, it did absolutely nothing for me and probably made my depression worse. It was like poison. And I think that if anyone has to suffer anymore than 4-6 weeks for their depression to subside, then that's entirely too long.
I'm not saying I derived no benefit from the drug early on (it definitely made life better), just that the greatest effect wasn't felt until beyond eight weeks. I agree that if you felt your depression worsening after 4-6 weeks on moclobemide, then it isn't the drug for you.
> . . If it doesn't work, there's no withdrawal for most people and you can start a new drug as soon as 24 hours after you stop it. Compare that with the withdrawal of the classic MAOIs and the 2 week washout period.
>
> "What" withdrawal from the classic MAOIs are you talking about?The same as the SSRIs... flu-like symptoms, etc. Actually, I found Nardil withdrawal to be the worst ever! (and I've been on a lot of drugs). Most of the time withdrawal isn't a big deal, but it's definitely nice to not have to deal with it. Considering moclobemide's lack of side-effects and dietary restrictions, I don't think it's illogical to give this drug a try before commiting to Nardil or Parnate. If it doesn't work, the next drug can be started as soon as 24 hours after stopping it. To me, that's worth trying...
Anyway, I'm glad to hear that Parnate has worked so well for you, and without any major side-effects. I know how horrible mental illness can be, and it's nice to hear you're doing well.
Jon :)
poster:JonW
thread:260754
URL: http://www.dr-bob.org/babble/20030917/msgs/262557.html