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re: MAOI and Ecstacy

Posted by pontiacfiero69 on September 22, 2003, at 23:35:09

In reply to re: MAOI and Ecstacy » pontiacfiero69, posted by lil' jimi on September 22, 2003, at 16:59:46

> i don't know, but this part sounded bad ... ...
>
> " These data suggest that the deamination by monoamine oxidase-B of excessive dopamine within the 5-HT terminal generates hydrogen peroxide that may lead to membrane lipid peroxidation, and perhaps other oxidative insults, resulting in selective 5-HT terminal degeneration subsequent to MDMA treatment. "
>
> ... sounds like that could hurt

Yes it does. However, if I understand the abstract correctly, the observed neurotoxicity and serotonin terminal degeneration appeared to be blocked by l-deprenyl.


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URL: http://www.dr-bob.org/babble/20030917/msgs/262546.html