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Lar, Re:thyroid replacement

Posted by tealady on September 2, 2003, at 22:52:47

In reply to Re: thyroid replacement and calcium carbonate » Larry Hoover, posted by tealady on August 31, 2003, at 1:32:23

Lar,
http://www.dr-bob.org/babble/20030828/msgs/255832.html
I found the Methocel info , if you are interested
http://www.colorcon.com/pharma/mod_rel/methocel/literature/Hydroph_Matrix_Broch.pdf

pp 13 of 37 ..graph..click on enlarge to 200% to see it!

All compounding pharmacies I have contacted so far all use METHOCEL E4M..which does look like the current optimal choice for the purpose.

Note thought that with ONLY 25% Methocel, specified percentage of the drug you which to slow release and LACTOSE ..to speed up the release ..you get only about 80% of the drug (THYROID) in 8 1/2 hrs or so...90% in 12 hrs ..and 93% in 14 hrs etc.
Think I've got the drug release rate pretty right as I confirmed with my body temperatures, which are sensitive enough to the thyroid meds to act as a gauge

Really appreciate all your help,

Jan



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poster:tealady thread:255272
URL: http://www.dr-bob.org/babble/20030902/msgs/256504.html