Posted by tealady on August 18, 2003, at 19:39:12
In reply to Re: N-acetyl tyrosine » andys, posted by Larry Hoover on August 4, 2003, at 7:47:20
Hi Larry,
Being probably the newest addition to your fan club<g>...yep, I am amazed at your knowledge level too.
Wondering about acetylation..
Does one get an acetylated form of (x) by mixing vinegar with (x)?
I find your posts very interesting , especially now I have just added tyrosine into my mix of thyroid meds, vitamins and minerals.I have a long history..mostly chronic fatigue and really cold hands,feet. Also always craved meat. I could eat a steak 3 meals a day. Also high thirst (perhaps due to the high protein).
Tried hypoglycemic diets(after a GTT test, 1985, with normal fasting blood sugar, reactive hypoglycemia dropping to borderline absolute levels) no effect.
Also tried 5 years of various SSRI's(1995-2000) no good effect, some scary side effects...like hand tremour, eye tics, altered perception of traffic speed...I started on long history of thyroid meds Aug01 ...some improvements, some worsening of symptoms.
I came across a "post"< http://forums.about.com/ab-thyroid/messages?msg=36074.1 >by someone who had added in phenteramine to their thyroid med mix hoping the dopamine would provide a missing bit of the picture. I thought of tyrosine..and that it too has a dopamine pathway..so I am trialling that.I am “starving” about 1/2 hour after I take say 7.5mcg of T3(slow release)..so I thought the dopamine in the tyrosine may block this “starvation” the T3 causes. Thyroid extract(contains T4 +T3 +) also causes an increase in hunger but not quite as pronounced..
I thought it looked like I was adding in only a bit of the picture and not the other bits..so I started adding in tyrosine to the mix to try to get some of the missing pathways..perhaps the dopamine to help with temperature and appetite suppression...and perhaps I needed to replace mor than the thyroid pathways if something was missing higher up in the chain.
The tyrosine appeared to help with the appetite and for the first 2 days just 500mg of tyrosine bought my body temp up about 1.2C to almost 37degrees..all day, although a sweat session around 4am in the morning managed to lower the temp again...both days.(stopped by adding in a tad of estradiol gel transdermally)
This temp rise only lasted for the first 2 days..on the 3rd, 4th day, it no longer seems to be working..darn
I will keep trying. I'm thinking I must have something wrong/missing I the way I break down protein or my body wouldn't have craved it so much all my life..so I need to find out where..hopefully by working backwards and replace the missing bits...right.
That is why I would favour trying tyrosine over phenylanaine for starters, less enzymes, links etc to go thru. If all the tyrsoine bits work, I guess then go back to the phenylanaine looking for more missing pieces..
I do have antiTPO, anti TG antibodies, a small thyroidwith nodules on ultrasound..which shows it has been struggling to keep up in my books..and when I was born my Mum had to give me antihistamines so I could breathe while sucking (little blue pills..phernergan I think)..so I do have something up with histamine response I guess tooI'm really struggling with all of this altrhough I have spent the past 2 1/2 years trying to research the net, like you said..a lot of stuff is pretty geekish and although I have figured out that "ase" on the end means enzyme, that's about it! I really need some courses, but I haven't found any so far to take me thru basic chemistry, biochem, physiol up to this level, lol.
Thaks for reading this,I know most detail has n been left out, ANY suggestions welcomed
Jan
poster:tealady
thread:246486
URL: http://www.dr-bob.org/babble/20030818/msgs/251960.html