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Re: St. John's Wort » Questionmark

Posted by Larry Hoover on June 22, 2003, at 8:54:30

In reply to St. John's Wort, posted by Questionmark on June 22, 2003, at 0:59:47

> Okay, i think i am pretty darn sensitive to psychoactive substances-- just about every drug that i can think of, legal or otherwise, i have always been quite sensitive to i think (with the possible exception of Paxil). But when it comes to nutrient supplementation and non-immediate-acting herbs (like say St. Johns Wort in contrast with ephedra), i have never been able to feel ANy effect or difference in mood whatsoever. i'm specifically curious about SJW, since that is usually supposed to have at least SOME effect.

So, I can assume no adverse effects, either?

> i have tried SJW on at least three occasions for at least a month each time and... absolutely nothing. i took the standard dosage of the typical formulation (300mg extract stndrdzd to 0.3% hypericin content 3x/day), if not more. Now i never tried the LI160 extract i don't think, but still, you'd think i would have noticed at least sOMe effect, right? Zanyone have any explanation or advice etc. for this?
> Thank you.

It is possible you were sold fraudulent products on each occasion. There have been a number of independent analyses of SJW products on the market in North America, and the outcomes are remarkably similar for each such analysis: about 1/3 of all products contain no, or less than 10%, of the labelled active ingredients, 1/3 contain substantially less than the labelled ingredients, and about 1/3 meet or exceed labelled concentrations.

Alternatively, you didn't use enough to obtain an effect in *your* body. There has never been a reported case of SJW overdose. It has been used, in preliminary research studies, at 22,000 mg/day as an antiviral in AIDS patients (since shown to be contraindicated due to induction of liver enzymes which clear other antivirals from the body). At 22,000 mg/day, sun sensitivity was an issue.

If you get some Kira or Perika, and they don't work, I'd say you'd have exhausted your options with SJW.

Lar

 

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poster:Larry Hoover thread:234747
URL: http://www.dr-bob.org/babble/20030619/msgs/235996.html