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Re: Lar, Re: Vitamins mineral for moods » McPac

Posted by Larry Hoover on June 21, 2003, at 8:02:59

In reply to Lar, Re: Vitamins mineral for moods, posted by McPac on June 20, 2003, at 23:12:31

> Lar, from the one study, "The special extract of St. John's wort, LI 160"

LI-160 is sold as Jarsin 300, or Kira, in the US.

http://www.aphanet.org/JAPhA/julyaug01pdfs/wurglics%20p560_566.pdf

The product in the above review known as Neuroplant is Perika in the US.

> >>>>>> Wonder what LI 160 is?

The article referenced above gives you an analysis of the content.

>I mean, sometimes I'll read that "X" is the extract that you need, other times maybe it's "Y" that is the important extract in SJW.....so if you go to a store and buy some SJW, are you going to get the proper extracts that you need for depression/ocd in ANY SJW bottle OR do you have to look for a specific extract formulation of SJW?

If you buy Kira or Perika, you're getting the German pharmaceutical-grade product.

>(hope you understand the gist of that question, lol) In other words, would one particular SJW formulation be best for depression, another formulation best for ocd, another formulation for something else? Or would ANY bottle of SJW suffice?

I have no idea which constituent would have the best effect on OCD. The open-label study just mentioned that it was standardized on hypericin.

> Lastly, I know that it's always said not to take SJW w/ an anti-dep. (serotonin syndrome)....I've also read websites where they'll say that true serotonin syndrome is very rare....now, lots of folks take multiple anti-dep's at once...and lots of folks take HIGH dosages of their anti-dep's...if I am only taking, say, a moderate anti-dep. dose, do you really think that the concern about taking an AD w/ SJW is as serious as some say?

I knew where this was going.....

Serotonin syndrome is a threat to life. It is a serious concern because it is serious. Under medical supervision, with a full awareness of the threshold (earliest) symptoms of serotonin syndrome, you could do it safely. On your own, without observation, I cannot suggest you do anything of the sort.

The good thing about SJW is that withdrawal of the drug quickly reverses the effects. But it is a drug, and should be given that respect.

>I mean, if one dude is taking 200 mg of Zoloft AND another decent dose of another AD, how is it that someone taking only 50 mg of only Zoloft should NEVER take it w/ SJW?

....without supervision....

>It would seem that some folks might be able to cut down on an AD dose if they could add the SJW to their AD? Is the serotonin syndrome scare as likely as the "warnings" claim? Thanks in advance for your thoughts!!!!!

It has been suggested, by renowned world expert Dr. Healey (sp?), that in cases of difficult SSRI withdrawal, that SJW is an option for easing the process. In that case, the dose of the replacement drug (SJW) is increased simultaneous to the decrease in the drug being withdrawn. This is a medically supervised process. Washout between drugs is clearly impossible under these circumstances, but great care is taken to consider the additive effects of the two substances.

You need to discuss this with your medical supporters. If you don't like their answer, you still need to find a medical supervisor for what you're considering. When you're dealing with psychoactive substances, you just can't trust your own judgment as a sole measure of what's really going on.

Lar

 

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poster:Larry Hoover thread:234747
URL: http://www.dr-bob.org/babble/20030619/msgs/235806.html