Posted by SLS on June 18, 2003, at 12:10:17
In reply to Re: BPD, GRK, and dopamine, posted by jrbecker on June 16, 2003, at 12:44:54
Hi JRB
> G-protein coupled receptor kinase (GRK-3) is largely responsible for modulation of dopamine activity.
Do you know in which direction the excitability of DA neurons is modulated by GRK-3? In other words, if the activity of GRK-3 is increased, how is DA neurotransmission influenced? Is the sensitivity or experession of DA receptors changed? Second messengers?
Thanks.
- Scott
poster:SLS
thread:234222
URL: http://www.dr-bob.org/babble/20030614/msgs/234801.html