Posted by jrbecker on June 16, 2003, at 15:04:16
In reply to Re: BPD, GRK, and dopamine » jrbecker, posted by jemma on June 16, 2003, at 14:12:48
Drugs or supplements that modulate dopamine (Requip, Stimulants, caffeine, NADH, tyrosine, wellbutrin [sometimes], even strattera [which affects DA]) make me tired too. At first, they rev me up, but then a rebound effect kicks in and makes me just shut down. I attribute this partly to the wicked feedback mechanisms in place that help to regulate dopamine's output. Secondly, dopamine plays contrasting roles for arousal in different parts of the brain. So because BPs are more sensitive to DA to begin with, it also means that screwing with its output will have more drastic effects.
I'm sorry that I don't have any real suggestion for you. My main strategy is to avoid most dopaminergic meds to begin with since they do more harm than good. For instance, if I take a stimulant, I really only get 2 good hours of focus and energy before I crash, and then become tired, irritable and anxious the rest of the day. I'm hopeful and confident that future drugs will be less adverse to this problem.
Research like this is definitely a step in the right direction.
JB
poster:jrbecker
thread:234222
URL: http://www.dr-bob.org/babble/20030614/msgs/234372.html