Posted by kotsunega on June 16, 2003, at 16:01:37
Zyprexa has sedating properties that the other atypical antipsychotics don't share to any real degree. What makes Zyprexa so sedating? I found an Aripiprizole receptor binding chart (http://sl.schofield3.home.att.net/medicine/aripiprazole_binding.pdf) that compares the receptor binding properties of Abilify to other atypical antipsychotics, but I don't see a relationship between the degree of binding for any receptor with Zyprexa, unless it's the 5HT1A receptor for which Zyprexa has a very strong affinity. Could this be what causes it's sedating action?
poster:kotsunega
thread:234389
URL: http://www.dr-bob.org/babble/20030614/msgs/234389.html