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Re: can anyone help with this? » avid abulia » ace

Posted by avid abulia on June 14, 2003, at 11:41:37

In reply to Re: can anyone help with this? » avid abulia, posted by ace on June 14, 2003, at 1:43:03

> Yes! An MAOI (Nardil or Parnate - I'd go Nardil first) Anafranil low dose (due to its problems with seizures).

i forgot anafranil is a TCA; yes, i did try that one, and at least unlike the new-school SSRIs, it just didn`t do all that much besides making me sleep about 16 hours each day (i was fine at night anyway, though). nardil is one i`d like to give a try, as one of its metabolites is a gaba-transanimase inhibitor so it may potentially reduce seizure risk. i`ve heard that combining low-dose nardil and low-dose elavil qhs at bedtime was safe-ish and effective for all aforementioned problems except seizure disorder, and the elavil reduced risk of hypertensive crisis because it blocks calcium channels and is a noradrenaline reuptake inhibitor so it reduces vascular response to tyramine, but i don`t know the seizure risk for elavil. i`d like to give it a try, but i have to convince my p-doc... and actually, nardil was the AD my epileptoligist mentioned would be okay, and the neurologist treating my migraines seemed to think elavil would be safe but wanted to give keppra a try first.

>Have you tried Zyprexa or any old typical APs? Any luck?

yeah--i had luck alright, and it was the real bad kind.

> But not just from my experience, but from the many, many, many anecdotes I've read I would say give Nardil a try. More thought but I'm about to be kicked out of my library (closing time!)
> All the best,
> Ace.

thanks for the thoughts! i`ve heard other places a lot of people who are refractory to other meds do very well on MAOIs, and i would really like to at least give it a try.

~AA


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