Posted by ace on April 29, 2003, at 23:55:23
In reply to Re: Serious Anafranil REM phenomenon, PLS answer! ?ace, posted by SLS on April 29, 2003, at 11:28:24
> Dear Ace,
>
> Starting Anafranil so soon after discontinuing an irreversible MAOI (Nardil) is contraindicated. I would recommend that you run a few Google searches using the term "serotonin syndrome", including quotes. Create a list of symptoms of the syndrome and carefully monitor yourself for their occurence. This might include body temperature (hyperpyresis). Muscle stiffness might be a good early indicator. I experienced some symptoms of serotonin syndrome when I added Nardil 60mg to imipramine 300mg. They resolved upon discontinuation of imipramine.
>
> You will most likely experience REM rebound for having discontinued Nardil so quickly. You might even dream before falling completely asleep.
>
>
> - ScottScott, the recommended period of washout betwwen Nardil and Anafranil is 10-14 days. I'm going for 10 'cause I'm at uni and cannot have a relapse or any extra symptoms set in. It definately won't after such a short peiod. I know this from experience. Usuallt takes about 4 weeks. I will start Anafranil at low dose 25mg for 2 days. I will be fine.
How long did you think my washout was for. In one (very good, technical monograph) it says 7 days between MAOI and TCA (including Nardil and Anafranil is fine)
Thanks for the reply!
Ace.
poster:ace
thread:223044
URL: http://www.dr-bob.org/babble/20030429/msgs/223337.html