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Re: Parnate - is it serotonin agonist

Posted by Caleb462 on April 3, 2003, at 22:02:39

In reply to Re: Parnate - is it serotonin agonist, posted by JackD on April 3, 2003, at 14:13:20

> YES! It ihibits the Monoamine oxidace that oxidizes the amino acids serotonin, norepinephrine, and to a smaller extent dopamine. It is NOT an agonist, that is the wrong terminology. An agonist is like Cocaine, for example, which directly mimics dopamine and is therefore a D1 (dopamine suptype 1) agonist cause it stimulates it DIRECTLY. MAOI's don't directly stimulate anything, they just allow your neurotransmitter levels to rise.

Well, you are also mistaken. Cocaine is not a D1 agonist. It is a reuptake inhibitor of Dopamine, Norepinephrine, and Serotonin.


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URL: http://www.dr-bob.org/babble/20030402/msgs/216034.html