Posted by cybercafe on April 1, 2003, at 0:35:26
In reply to Re: Is Zyprexa a serotonin agonist or antagonist? » cybercafe, posted by zeugma on March 30, 2003, at 20:45:51
> > > That's good to hear. I believe you have been dx with ADD? Was the Parnate helpful for this disorder?
> >
> > i'd say no.. but it was a lot better than feeling depressed.hmmm... i did only take 30 mg of parnate.. and then i added zyprexa, so maybe that's to blame
but i found 40 mg of ritalin SR helped me concentrate a bit better ... it's hard to say, cuz neither one really worked :)
so maybe parnate would work for you
> The reason I asked was because Parnate is often called "amphetamine-like" and it has been claimed that it metabolizes to amphetamines (there was a recent controversy about this on this board). I have severe inattentive ADD and am interested in any possible meds for this condition; I know MAOI's are used as a 'last-resort' option for ADD sometimes and Parnate seems like the logical choice.
parnate seemed like a more "powerful" med... not just in knocking out depression... but i know it would give me insomnia whereas with ritalin i can still sleep 14 hours a day.. so in a really obvious way, it seemed more stimulating to me...
> > hmmm.. i notice an antidepressant effect after i take 2.5 mg zyprexa ... maybe it's a placebo effect... or maybe when 5HT2A receptors are blocked there's enough to hit 5HT1A and other good receptors ... who knows
> >
>
> Zyprexa is probably helping with your depression as well as any other problems. Drug 'classification' to a large degree is arbitrary...in fact antipsychotics have been shown to have efficacy in depression. A drug like lithium can help people with unipolar depression, too, even though it's classed as a mood stabilizer.yeah .. i think it's really important to try and understand the underlying mechanisms in why something works, so we can make predictions about our future responses to meds (because we neither have time to try all the hundreds of meds out there nor do we want to endure all the washout periods and ineffective drug trials)
poster:cybercafe
thread:213675
URL: http://www.dr-bob.org/babble/20030329/msgs/214953.html