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Re: Is Zyprexa a serotonin agonist or antagonist?

Posted by cybercafe on March 28, 2003, at 16:47:02

In reply to Is Zyprexa a serotonin agonist or antagonist?, posted by ace on March 28, 2003, at 0:58:41

> I've heard conflicting reports on this.
>
> Whats the real 'lowdown'?
>
>
> Ace.

zyprexa is a serotonin 2A antagonist which makes it a serotonin agonist

i.e. when serotonin is blocked from binding to the 2A receptors, there is more available in the synaptic cleft to bind to receptors that don't suck (2A sucks)

where the definition of suck is - causes sexual dysfunction, anxiety, hallucinations, nausea and so forth

i think 5ht2a receptors are the crappiest serotonin receptors
i think 5ht1a post-synaptic receptors are the coolest receptors

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poster:cybercafe thread:213675
URL: http://www.dr-bob.org/babble/20030325/msgs/213865.html