Posted by Shawn. T. on March 30, 2003, at 20:16:20
In reply to bcl-2 expression - HELP, posted by linkadge on March 30, 2003, at 19:02:15
Yes. Here's a good definition:
"expression: The cellular production of the protein encoded by a particular gene. The process includes transcription of DNA, processing of the resulting mRNA product and its translation into an active protein. N.B. A recombinant gene inserted into a host cell by means of a vector is said to be expressed if the synthesis of the encoded polypeptide can be demonstrated." [IUPAC Bioinorganic, IUPAC Compendium]
-That should explain expression, transcription, and translation; you'll see those three terms used regularly. As a side note, I don't believe that increased bcl-2 activity is responsible for lithium's efficacy in bipolar disorder; its inhibitory effects on protein kinase C (PKC) alpha are probably much more important.
Shawn
poster:Shawn. T.
thread:214547
URL: http://www.dr-bob.org/babble/20030329/msgs/214571.html