Posted by MB on December 13, 2002, at 11:47:21
In reply to Re: Can Klonopin decrease AD efficacy? » MB, posted by Ritch on December 13, 2002, at 0:28:54
> > I've been on Wellbutrin (again) along with Klonopin to take the *edge* (rage, anxiety, panic, neck cramps, blurry vision) off of the Wellbutrin. Anyway, the depression isn't any better. Could it be that the Klonopin is keeping the Wellbutrin from working? I've heard that benzos can make depression worse (except for Xanax...why *is* that by the way, why is Xanax different?).
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> > MB
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> > Oh, anyway, the doc says maybe Nardil next since SSRIs don't do well by me. Exactly how fat should I expect to get if I take Nardil (I gained 40 lbs on Paxil). I don't like the SSRIs because, after the akathisia (RLS), teeth grinding, neck cramps, headache, insomnia, tachycardia, and sweats are behind me I'm left an emotionless, fat, 14-hr-a-day sleeper who can't have an orgasm. Should I expect Nardil to be any better? I've also thought about ECT, shooting myself in the head, or becoming a heroin addict.
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> > Any advice?
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> > MB
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> Hey, Wellbutrin caused rage/anxiety/panic for me as well (and at doses of just 37.5mg or higher-even with Depakote on board). Before reaching for the pistol or the needle, I would reconsider Wellbutrin as your primary antidepressant (you said it wasn't working anyways). I've found with time that taking another med to *counter* something the first one caused hasn't worked very well (augment.. that's a different story).
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I've been reading that there is an availability issue with Nardil, so I may not go that route either. I can't handle anything that blocks H-1 receptors (which brings on the restless leg syndrome I've had since a kid) so the tricyclics are kinda out (plus, I can't even take Allegra or Zyrtec, the "non-drowsey" antihistamines, without passing out for days on end). The only thing left for me to try is the MAOI thing. I'm doing this through my GP, so anything experimental like taking a stim with memantine (to avoid tolorance and dependence like last time) or trying a foreign drug like moclobemide is out of the question. Looks like it's Parnate or ECT or au natural. You know, now that I think of it, I haven't been chemical free for over 15 years...and what I mean by that is no p-meds, no rec-drugs, no caffeine, no alcohol, no psychotropics of any kind. I wonder what would happen if I just tapered off of EVERYTHING.I agree with you about taing meds to counter the untoward effects of other meds. The problem is that they all cycle in the system with different frequencies. I might need Klonopin to take the edge off of Wellbutrin SR, but if I take them at the same time, I'm going to be all over the place emotionally (i.e., at times the K levels will be low while the WB levels will be high; the K levels will be high while the WB levels are low; sometimes they'll both be in that perfect ratio; etc.) What I've been noticing is that I have violent rages with suicidal/homicidal ideation in the morning. These subside into relative normalcy by 10 AM. Then, by early afternoon, all I can do is cry like a baby...over nothing, really...I just weep like a school girl. Then around dinner time I'm back to relative normalcy with a tinge of hypomania. Then to bed to start the cycle over again. I'm almost SURE it is linked to the way the the ratios of the two drugs cycle over a 24 hr period. Plus, I still haven't been able to kick my caffeine habit, which makes this whole thing impossible to figure out.
Plus, I'm so indecisive. Yesterday, I got that horrible AD dulling effect (the one where it feels like someone has drilled a hole in your forehead and filled your cranium with sand). Different than the Klonopin drowseys...I'm talking about that **sub-hallucinogenic-LSD-dose-put-me-on-the-short-bus-and-tie-my-shoes-for-me-what's-that-word-I-can't-remember** feeling. And I said, that's f*cking it, I want this crap out of my system. Then this morning, I think, "well, maybe it's helping a little," so I popped a WB tablet. I can't make up my mind and I'm rambling so I must not be *depressed* depressed, but it all seems so complex and difficult and not worth the effort and I just wish I didn't have go through the meaningless motions.
MB
poster:MB
thread:131530
URL: http://www.dr-bob.org/babble/20021210/msgs/131659.html