Posted by oracle on November 17, 2002, at 22:51:57
In reply to Need meds fast -- AUGH!, posted by bookgurl99 on November 17, 2002, at 22:34:20
Pharmacokinetics:
Following multiple oral once-daily doses of 200 mg, the mean peak plasma concentration (C(max)) of sertraline is 0.19 mcg/mL occurring between 6 to 8 hours post-dose. The area under the plasma concentration time is 2.8 mg hr/L. For desmethylsertraline, C(max) is 0.14 mcg/mL, the half-life 65 hours and the area under the curve 2.3 mg hr/L. Following single or multiple oral once-daily doses of 50 to 400 mg/day the average terminal elimination half-life is approximately 26 hours. Linear dose proportionality has been demonstrated over the clinical dose range of 50 to 200 mg/day.I think you can miss a day and not have any problems. I would ask your new doc for a few days
to cover you till your visit.
poster:oracle
thread:128072
URL: http://www.dr-bob.org/babble/20021116/msgs/128075.html