Posted by Shawn. T. on July 24, 2002, at 18:24:28
In reply to downregulation??, posted by turalizz on July 23, 2002, at 10:18:30
Everything that I've read about this issue so far has been less than satisfying. I finally found a good explanation, however. I posted something earlier about up/down regulation that was incorrect based on this knowledge by the way. I was misled by some studies that seemed to agree with what I was saying. I know that this page is hard to understand, so feel free to ask me questions if you don't understand something. It pretty much makes everything about fifty times more complicated, but it also means that we now know how to make some incredibly selective drugs (I don't use selective as in the context of selective serotonin reuptake inhibitors, SSRI is pretty much a contradiction of terms). It's going to take me a while to sift through all of their research.
http://www.camh.net/research/research_ar2000/molecular_pharmacology.html
poster:Shawn. T.
thread:113408
URL: http://www.dr-bob.org/babble/20020718/msgs/113569.html