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Re: what do you think about clonidine » katekite

Posted by fachad on July 20, 2002, at 19:03:58

In reply to what do you think about clonidine, posted by katekite on July 20, 2002, at 18:07:06

>But I am less interested in trying trimip. now that I've heard that it has significant anti-cholinergic effects.

I don't get any anti-cholinergic side effects from trimipramine as long as I keep the dose low. Even at 12.5 mg I did not get any drying.

Chole was being tortured by anti-cholinergic effects from Amitriptyline and they were much less when she switched to doxepin.

Keeping the dose low enough is the key.

As for clonidine, I considered that myself, but I don't think it's a good idea because you are messing with blood pressure regulation, and that could precipitate problems later on.

I still think very low dose TCAs are the best sleep meds, but other alternatives with little to no anti-cholinergic activity include trazodone, Ambien, Sonata and of course the benzodiazepines.

Popular benzos for sleep include Lorazepam, Temazepam, and Klonopin.

> Yeah the doc didn't want to mess up hormone tests. But I think this is dumb reasoning because I just started the BC pill which messes up hormones, I will have to wash out of everything before tests resume anyhow. But I am less interested in trying trimip. now that I've heard that it has significant anti-cholinergic effects.
>
> Since Remeron worsens my hot flashes I will not take it again. Especially since the 7.5 mg dose was not enough to make me sleep better than without it but my eyes still don't quite focus. I would have been better off with Vistoril or Benadryl.
>
> What are some alternatives that have no anti-cholinergic activity? Clonidine maybe? Any other ideas?
>
> thanks -- kate


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