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Re: Wellbutrin extrapyramidal effects? LostBoy » Anna Laura

Posted by JohnX2 on June 26, 2002, at 18:37:53

In reply to Re: Wellbutrin extrapyramidal effects? LostBoy, posted by Anna Laura on June 26, 2002, at 8:58:52

> > I never got any EPS symptoms from Wellbutrin SR when I took it years ago. However, I did get EPS type symptoms from Ritalin when I took that. Ritalin and Wellbutrin are kind of similar, with Ritalin being more potent of course. But I could see some people getting EPS type symptoms from Wellbutrin. With drugs...ANYTHING is possible.
> >
> > On Ritalin, my muscles got tight and stiff feeling much the same as I get when I take atypical anti-psychotics. I dont know why.
> >
> > Anything is possible on drugs, so if youve been on Wellbutrin for a while and are having stiff muscles and stuff like that, twitching and stuff, it would be time to tell your doctor about it.
>
>
>
> I don't have any stiff muscles and stuff like that
> fortunately; my tongue keeps on twitching once in a while though.
> I had a similar problem with Tofranil(imipramine); i usually get this twitching thing when the good effects of the drug are about to fade away : when the twitching goes away, the good effects also desappear .
>
>
> P.S.
>
> I called my pdoc but he didn't return my calls.

That paper on 2d6 phenotype hypothesis of ad extrapyramidal effects
lists a few references:

1. A case of oral dyskinesia associated with
imipramine treatment. Am J Psy. 1977; 134 (11) 1297-1298

2. Desipramine induced oral-pharyngeal disturbances:
stutterting and jaw mycoclonus. J Clin Psychopharm
1992; 12(6): 44-45

A bunch more on tricyclics... (2d6 meds).

John


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