Help,Li vs. Zyprexa vs Lamictal for manic symptoms

Posted by JohnX2 on April 15, 2002, at 20:16:30

I was wondering how lithium stacks up against Zyprexa and Lamictal for particular (hypo)manic symptoms.
particularly (more mild symptoms):
- psychomotor agitation
- anxiety
- anger
- racing thoughts
more severe symptoms (fleeting):
- paranoia (feelings of conspiracies, etc)
- derealization/depersonalization/detachment
- grandiose thought patterns
- bad insomnia
- intense rage
- violent mood swings

I like to just take zyprexa with my Lamictal/Topamax/Serzone since Zyprexa fixes the lingering problems quite nicely and closes the book. But I got the TD (dystonia) in my hand (a clenching) and restless legs so I try to avoid zyprexa, despite how wonderful it is. BTW, the residual TD symptoms from prior high dose Zyprexa administration have all but disappeared.
I'm in the process of getting some lab testing done in preperation for Lithium trial, so i was wondering what I may expect.
One thing I think is happening is that the Topamax is the culprit in these wild manic swings, as lowering the dose has decreased the symptoms substantially. I was thinking maybe I could dump or lower topamax, raise Serzone (because either med is to treat myofacial pain and depression, and I *don't* think Serzone of the 2 makes me (hypo)manic), and possibly bump Lamictal dose up.
Previously bumping Lamictal above 150 mg would make the myofacial pain worse (is Lamictal a SRI at higher doses, SRI activity this seems to correlate to my pain)? But maybe with the strong Serzone (blocks bad serotonin receptors), then I can tolerate stronger Lamital (knock out the bad cycling).
I think the stronger dose of Serzone has some of the beneficial anti-serotonin 5-ht2 receptor qualities that the additive Zyprexa was giving me.
As you can see I am grasping to avoid Li. I don't know why???, Maybe I just don't think I can deal with side effects. Pooped out from medicine trials. Are the LI side effects really that bad? The PDR scares the shit out of me.
These bad (hypo)manic symptoms are out of line for me and I really think they are Topamax related.
Sorry for the ramble.
Thanks for any input.
John

Thread

Help,Li vs. Zyprexa vs Lamictal for manic symptoms JohnX2 4/15/02
Re: Help,Li vs. Zyprexa vs Lamictal for manic symptoms » JohnX2 Ron Hill 4/15/02
Re: Help,Li vs. Zyprexa vs Lamictal for manic symptoms rainbowlight 4/15/02
Re: Help,Li vs. Zyprexa vs Lamictal for manic symptoms » JohnX2 Ritch 4/15/02
Re: Help,Li vs. Zyprexa vs Lamictal for manic symptoms JohnX2 4/16/02
Re: Help,Li vs. Zyprexa vs Lamictal for manic symptoms » JohnX2 Ritch 4/16/02
Lamictal - rainbow light Bekka H. 4/17/02
Re: Update JohnX2 4/17/02
Re: Lamictal - rainbow light » Bekka H. JohnX2 4/17/02
Bekka - I take Restoril rainbowlight 4/17/02
Re: Update » JohnX2 judy1 4/17/02
P.S. from Judy judy1 4/17/02
Re: Update » judy1 JohnX2 4/17/02
Re: Lamictal - Johnx2 Bekka H. 4/17/02
Re: Bekka - I take Restoril -- rainbow light Bekka H. 4/17/02
Bekka JohnX2 - I started on 50 mgs. of Lamictal rainbowlight 4/17/02

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