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Re: Parnate - Side Effects? » JEANIE

Posted by dennison on April 10, 2002, at 22:07:07

In reply to Parnate - Side Effects?, posted by JEANIE on April 10, 2002, at 20:47:25

Jeannie--I've taken parnate for several years --the flushing is from vasodilation. Parnate blocks the sympathetic system which constricts blood vessels and maintains bloodpressure---without the sympathetic innervation -blood vessels dilate,hence the flushing and low bloodpressure. Low bloodpressure can make your head pound --make sure you maintain fluid intake and salt. Also be weary of histamine containing foods such as tomatoes they have a considerable amount of histamine and histamine is a powerful vasodilator. Remember histamine is a "mono" amine too and of course parnate is a mono-amine-oxidase-inhibitor so histamine isn't brokendown as it normally would be. I think you'll find that the biggest problem with maoi's is indeed the "Low" bloodpressure effect. Divided doses helps and make sure to definitely maintain hydration with adequate water intake last thing you need is dehyration contributing to the already lowerred bloodpressure!!!!!!!


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