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Re: SLS (Scott), anti-poopout agents?

Posted by johnX2 on March 13, 2002, at 16:16:05

In reply to SLS (Scott), anti-poopout agents?, posted by johnX2 on March 13, 2002, at 16:14:28


worked for someone:

http://www.dr-bob.org/babble/19990201/msgs/2821.html


>
> Have you seen this Naltrexone anti-SSRI poop-out tip in the pbabble tips section? It look kind of hoky.
>
> But Naltrexone is an opioid-antagonist.
> And as you may now, these NMDA antagonists involved in synaptic plasticity mitigate opioid
> tolerance.
>
> So I don't if this is some kind of a "work-backwards" ploy but it looks intriguing.
>
> Btw, did you know that the 5ht-2 receptor is gated to NMDA conductance?
>
> Also, amphetamine releases serotonin via a diffusion mechanism at serotonin receptors.
>
> This whole poop-out thing is tied together in
> my shoot from the hip view.
>
> Maybe need more poop-out stabilizers?
>
> Something atypical:
>
> Naltrexone, Memantine,
>
> This other medicine Acamprosate (a GabaB med + NMDA antagonist) is fast track FDA approval for
> alcoholism for Forest Labs and is being looked at also for treatment resistant bipolar disorder (it is available in europe).
>
> I also saw some good darts at calium channel
> blockers like nimodipine.
>
> Still curious about this Naltrexone dude.
> Maybe you can reach that guy by email and find out what his thinking is?
>
> Best wishes,
> John


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poster:johnX2 thread:97813
URL: http://www.dr-bob.org/babble/20020313/msgs/97814.html