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Re: Tenex, Clonidine, Norepinephrine

Posted by JohnX2 on March 6, 2002, at 23:00:09

In reply to Re: Tenex, Clonidine, Norepinephrine » JackD, posted by JohnX2 on March 6, 2002, at 22:39:47


Sorry, I read your post so fast I default assumed
ADD symptoms (damn seen so many bpii stories , same here).

Sound like you should be on track if you just add in
a good mood stabilizer like Depakote, Lithium, Tegatrol,
Lamictal. You really should talk to your doc about a
bipolar II dx? A lot of times people kinda waffle over
if the anxiety/ADD symptoms are hypomania related.
Sometimes you can be hypomanic/agitated but not "euphoric"
its called a "mixed" state. Hard to differentiate from anxiety
and ADD symptoms. A lot of times the mood stabilizer will
fix the ADD and anxiety like symptoms by reducing your
agitation. The mood stabilizer often fixes the antidepressant
poop out problems. Also MANY PDOCS including my own prefer
to not even use an antidepressant for bipolar. They feel a mood
stabilizer alone will usually work! Lamictal and lithium have
very good stand alone AD/stabilizer properties.

Talk this over with your pdoc.

Best of luck,
John

>
> Hi,
>
> My thoughts...
>
> Paradoxical reaction? You probably need a mood stabilizer.
>
> I got the same crud. Maybe stealth bipolar II.
>
> Any hypomanic/ADD like symptoms? (You seem to be up on the terminology).
>
> How about Lamictal for starters (good AD action)?
> Depakote, Trileptal, Lithium the other standbys.
>
> More important than what I think,
> what's your doctor thinking about your reactions?
>
> -John
>
>
> > I've come to realize that the major component to my depression is norepinephrine related through emprical evidence. I have ADD, anxiety, and depression. I am currently on Concerta 18mg a day, Klonopin 1mg a day, and Remeron 30mg a day. I have just restarted Remeron after taking a 2 month break from it. It worked extremely well but then made me even more depressed than I was before taking it. Wellbutrin made me cycle from hypomania to depression, as did Effexor, even at very low doses. I have responded to just about every antidepressant I've tried, and always extremely quickly (especially the NE active ones) and robustly. These include Wellbutrin, Remeron, Effexor, and Paxil.
> >
> > My questions to the group are: Has anyone taken Clonidine or Tenex and experienced antidepressant action? I figure since NE reuptake inhibitors or antagonists cause strong and often paradoxical reactions, maybe NE agonists may be of some use. Also, why do Norepinephrine acting AD's cause me to cycle so? Am I bipolar? Wellbutrin and Effexor especially are always described as having very low potential in causing cycling in bipolar individuals.
> >
> > Can anyone shed some light on my strange reactions to meds and NE? Thanks!


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