Posted by JackD on March 6, 2002, at 22:20:19
I've come to realize that the major component to my depression is norepinephrine related through emprical evidence. I have ADD, anxiety, and depression. I am currently on Concerta 18mg a day, Klonopin 1mg a day, and Remeron 30mg a day. I have just restarted Remeron after taking a 2 month break from it. It worked extremely well but then made me even more depressed than I was before taking it. Wellbutrin made me cycle from hypomania to depression, as did Effexor, even at very low doses. I have responded to just about every antidepressant I've tried, and always extremely quickly (especially the NE active ones) and robustly. These include Wellbutrin, Remeron, Effexor, and Paxil.
My questions to the group are: Has anyone taken Clonidine or Tenex and experienced antidepressant action? I figure since NE reuptake inhibitors or antagonists cause strong and often paradoxical reactions, maybe NE agonists may be of some use. Also, why do Norepinephrine acting AD's cause me to cycle so? Am I bipolar? Wellbutrin and Effexor especially are always described as having very low potential in causing cycling in bipolar individuals.
Can anyone shed some light on my strange reactions to meds and NE? Thanks!
poster:JackD
thread:96815
URL: http://www.dr-bob.org/babble/20020301/msgs/96815.html