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Re: mod-/adrafinil with MAOIs

Posted by Elizabeth on February 26, 2002, at 21:04:18

In reply to Re: mod-/adrafinil with MAOIs » Elizabeth, posted by shelliR on February 26, 2002, at 9:51:23

> On nardil, I was fine on provigil (prescribed by my pdoc), but she recommended against the combination of nardil with adrafinil. Sure enough, I had my first (and only) hypertensive reaction with that combination. I would be careful if you decide to combine those two drugs.

I've had lots of mild (i.e., not dangerous)hypertensive episodes, including when I tried taking modafinil while on Parnate. I think this is rather common. Do you know how high your blood pressure got when you took the adrafinil?

Also, does anyone have any idea what pharmacological differences there might be between modafinil and adrafinil? I'm sort of thinking that Shelli's doctor might have recommended extra caution with adrafinil because s/he [the doctor] wasn't very familiar with it (since adrafinil isn't marketed in the U.S.), rather than because of any inherent differences between the drugs.

-e


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