Posted by mdertinger on February 24, 2002, at 13:04:40
In reply to Re: Help!-Compromised Liver Needs AD » mdertinger, posted by TSA West on February 23, 2002, at 20:58:58
> The possibility that patients with liver disease might not metabolize antidepressants effectively is most important clinically with TCAs, because toxicity occurs at blood levels only two to three times the therapeutic level. SSRIs, bupropion, and venlafaxine are also metabolized extensively in the liver, but they have a much wider therapeutic index. Lower or less frequent doses are recommended for patients with cirrhosis or liver impairment. Definitely get a second opinion or even a second permanent doctor.
Thanks for your note. Can you tell me what TCA means?
poster:mdertinger
thread:95206
URL: http://www.dr-bob.org/babble/20020222/msgs/95314.html