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Re: Can't sleep from Wellbutrin » mdertinger

Posted by Ritch on February 21, 2002, at 23:28:08

In reply to Can't sleep from Wellbutrin, posted by mdertinger on February 21, 2002, at 14:57:38

> I was recently prescibed 150 mg Wellbutrin in addition to the 80 mg of Prozac I've been taking for 7 years. The Prozac just didn't give me enough energy, although my depression was at bay.
>
> The Wellbutrin has been great. Lots of energy, but I'm having a hard time falling asleep at night. I've resorted to taking Xanex before bed, but I know if I keep that up I'll become addicted.
>
> I tried Remeron before Wellbutrin, but gained 20 pounds. I tried Serazone at night, but I was groggy all day.
>
> Anyone got advise?

Hi, I am having similar type of problems with Wellbutrin. The trouble is that its active metabolite takes about six hours to peak and then has a fairly long half-life (up to a day I think). Since WB is a lot like a stimulant that could explain a lot of the insomnia. Some people have tried taking their dose right before bedtime and seem to sleep OK (paradoxically) and then get up easily in the morning without a lot of grogginess. You might try it and see what happens. I did, but I woke up *too* early.

Mitch


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URL: http://www.dr-bob.org/babble/20020215/msgs/95059.html