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Re: An SSRI such as Zoloft would work better for you » 3 Beer Effect

Posted by DINGBAT on February 9, 2002, at 8:10:05

In reply to Re: An SSRI such as Zoloft would work better for you, posted by 3 Beer Effect on February 9, 2002, at 3:13:20

Hi 3 Beer - If you don't mind, please could you fill me in a little re: Mirapex (vs selegiline)? I live in South Africa and would like to see if it is available here (and, more importantly, if it would help me). Also, I've tried Paxil and had severe anorgasmia. In your opinion, would Celexa be more likely to help without the sexual side-effects?

Thanx!

> >Just because 5-HTP or St. John's Wort didn't work for you does not mean that Zoloft or Paxil would not. I've given myself fair trials of both 5-HTP & St. John's Wort & neither of them did anything! I have found that Herbs & supplements very often do not work & often are a waste of money & simply do not work as well as SSRIs. SSRIs are much stronger medicines than supplements or herbs.
>
> As far as sexual side effects go, Zoloft does not affect the ability to get it up but it just makes you last longer. The people in which SSRIs cause sexual dysfunction are mostly middle aged married men who have trouble ejaculating without popping a Viagra! In a teenage male (most of whom suffer from premature ejaculation) it should be a godsend! I am 23 & before Zoloft I was a 2 minute man, but while taking Zoloft I could last over a half an hour- a sex god!- ask women which man they would prefer! It also appears to make orgasms more intense.
>
> I have been reading about psychopharmacology for about a year now, & with your agitated state the last thing you need is a dopaminergic. Increases in Dopamine help concentration & motivation, but also can cause agitation, insomnia, & in high doses schizophrenic like paranoia. (In fact severly agitated depressives are often given anti-depressants or atypical anti-psychotics that block the actions of dopamine). I previously thought Zoloft may help you since it does have some dopamine reuptake inhibition properties, but it, along with Prozac are the most 'activating' of the SSRIs & often cause insomnia. With your agitation & insomnia you would be better off with Paxil, Celexa or Remeron. (Of the SSRIs Paxil has the worst sexual side effects & Celexa the least side effects).
> Remeron has no sexual side effects whatsoever,& it seems to be pro-sexual- 30 or 45 mg are a good starting dose, the higher the dose the less sedating Remeron is- don't take 15 mg it is too sedating. If you find 45 mg is too sedating up to 60 mg can be used & has virtually no side effects).
>
> If you are prescribed an anti-depressant please do not take Selegeline (l-deprenyl) in addition to it because it can result in a very serious drug interaction (See PDR).
>
> If you absolutely are set on taking a dopaminergic Mirapex is a far better choice & is actually used as a dopaminergic anti-depressant while L-Deprenyl is used for this purpose very rarely, if ever.
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> Your response to Adderall is not necessarily similar to the response you will have to a dopaminergic. Adderall releases & blocks the reuputake of BOTH Norepinephrine & Dopamine. Wellbutrin is a norepinephrine & dopamine reuputake inhibitor. Ritalin works as a relatively selective dopamine reuptake inhibitor. If you had a poor response to Ritalin, your response to l-deprenyl will probably just as bad (or worse since l-deprenyl lasts longer). Also, keep in mind that l-phenylalanine increases agitation & insomnia & nervousness.
>
> I think you are making a mistake that is going to result in more anger & agitation. I think either Zoloft, Paxil, Celexa or Remeron 30-45 mg would be a much better choice for you but it often takes people trials of many different medications before they find the right combination. Zoloft or Paxil will help you to be more sociable, funny, & popular- especially with girls, while Remeron will calm down your agitation/anger/anxiety & gives most people the best-quality sleep of their life.
>
> If you have health insurance, I would ask your general doctor for a referral to a psychiatrist. I have a feeling that it is going to take awhile to find the right combination to treat your problems & general doctors are simply not knowledgeable enough about psychiatric medications to help you effectively.
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poster:DINGBAT thread:93294
URL: http://www.dr-bob.org/babble/20020208/msgs/93407.html